Fig. 1 · Structure

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CDK4-IN-4

CDK4 Inhibitor

CDK4-IN-4 is a selective inhibitor of Cyclin-dependent kinase 4 (CDK4), with an IC50 value of less than 10 nM. This compound plays a critical role in cancer research by selectively interfering with cell cycle regulation, thus inhibiting the proliferation of cancer cells. CDK4-IN-4 is suitable for studies focusing on cell cycle dynamics and the therapeutic potential of CDK4 inhibition in various cancer models.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3027994-03-9
Applications CDK4 Inhibitor
Formula C23H25ClFN5O2
Molecular Weight 457.93
SMILES
FC1=C2C(C3=C(CC(C)(NC3)C)C=N2)=CC(C4=NC(N[C@H]5[C@@H](COCC5)O)=NC=C4Cl)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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