Fig. 1 · Structure
Documents & Downloads
CDK5-IN-1
CDK Inhibitor
CDK5-IN-1 is a selective inhibitor of cyclin-dependent kinase 5 (CDK5), exhibiting an inhibitory concentration (IC50) of less than 10 nM. This compound demonstrates over 100-fold specificity for CDK5 compared to CDK2, making it a valuable tool for studying CDK5-related pathways. CDK5-IN-1 is applicable in research on kidney diseases and offers insights into the molecular mechanisms governing renal function and pathology.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2639540-19-3 |
| Applications | CDK Inhibitor |
| Formula | C24H25FN6O3S |
| Molecular Weight | 496.56 |
| SMILES | O=S(C1=CC=C2C=NC(NC3=CC=C(N4N=C(CO)C=C4)C=C3F)=CC2=N1)(C5CCN(CC5)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.