Fig. 1 · Structure
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CDK7-IN-18
CDK7 Inhibitor
CDK7-IN-18 is a potent inhibitor of cyclin-dependent kinase 7 (CDK7). This pyrimidinyl derivative exhibits significant potential in the investigation of various cancers, particularly those associated with transcriptional dysregulation. CDK7-IN-18 serves as a valuable tool for research applications focused on understanding tumorigenesis and exploring therapeutic strategies targeting CDK7-mediated pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2765676-81-9 |
| Applications | CDK7 Inhibitor |
| Formula | C22H24F3N7OS |
| Molecular Weight | 491.53 |
| SMILES | CC1(CC[C@@H](CN1)NC2=NC=C(C(C3=CNC4=C(C=CC=C34)S(C)(=O)=NC#N)=N2)C(F)(F)F)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.