Fig. 1 · Structure
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CDK7-IN-22
CDK Inhibitor
CDK7-IN-22 is a selective inhibitor of cyclin-dependent kinase 7 (CDK7) with demonstrated antitumor activity. Its inhibition of CDK7 plays a crucial role in modulating transcriptional regulation and cell cycle progression, making it a valuable tool for cancer research. CDK7-IN-22 is suitable for studies on tumorigenesis, therapeutic resistance, and cellular proliferation pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2173190-60-6 |
| Applications | CDK Inhibitor |
| Formula | C22H25F3N6 |
| Molecular Weight | 430.47 |
| SMILES | FC(F)(C1=CN=C(N[C@H]2CCCNC2)N=C1C3=CNC4=CC(N5CCCC5)=CC=C34)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.