Fig. 1 · Structure

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CDK7-IN-25

CDK-7 Inhibitor

CDK7-IN-25 is a potent inhibitor of cyclin-dependent kinase 7 (CDK7) with an IC50 of less than 1 nM. This compound plays a critical role in regulating transcription and cell cycle progression, making it a valuable tool in cancer research. CDK7-IN-25 can be utilized to investigate the effects of CDK7 inhibition on tumor cell proliferation and survival, as well as to explore its potential therapeutic applications in oncology.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2009209-60-1
Applications CDK-7 Inhibitor
Formula C33H32N6O3
Molecular Weight 560.65
SMILES
O=C(C1=CC=C(NC(C=C)=O)C=C1)NC2=CC3=CC(NC4=NC(C5=CC(OCC/C=C/CN(C)C3)=CC=C5)=CC=N4)=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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