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CDK7-IN-28

CDK7 Inhibitor

CDK7-IN-28 is a potent inhibitor of cyclin-dependent kinase 7 (CDK7) with an IC50 value of less than 5 nM. This compound effectively impedes cell proliferation in the MDA-MB-468 cell line by interfering with cell cycle progression and inhibiting DNA replication. Its activity makes it a valuable tool for research into cell cycle regulation and cancer therapeutics.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3034082-58-8
Applications	CDK7 Inhibitor
Formula	C₂₃H₂₇F₃N₆O
Molecular Weight	460.50
SMILES	FC(F)(C1=CN=C(N=C1C2=CNC3=C2CCCN(C3=O)C4CC4)N[C@@H]5CNC6(CC5)CC6)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.