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CDK7-IN-32

CDK7 Inhibitor

CDK7-IN-32 is a potent inhibitor of Cyclin-dependent kinase 7 (CDK7), a key regulator of cell cycle progression and transcriptional regulation. This compound effectively disrupts CDK7 activity, leading to decreased phosphorylation of its substrates and subsequent modulation of cellular proliferation and survival. CDK7-IN-32 is utilized in cancer research and studies investigating the role of CDK7 in transcriptional control and therapeutic resistance.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2055741-42-7
Applications	CDK7 Inhibitor
Formula	C₂₄H₃₅N₅O₂Si
Molecular Weight	453.65
SMILES	O=C(N1CC2=C(C1(C)C)NN=C2NC(C3([Si](C)(C)C)CCC3)=O)NC4=CC(C)=CC=C4C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.