Fig. 1 · Structure
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CDK8 ligand 1
Ligand for Target Protein for PROTAC
CDK8 Ligand 1 is a selective ligand for Cyclin-Dependent Kinase 8 (CDK8), a crucial regulator of transcriptional activity. This compound is instrumental in the development of proteolysis-targeting chimeras (PROTACs), enabling targeted degradation of protein substrates. Researchers can utilize CDK8 Ligand 1 to create customized molecular tools for studying CDK8-mediated signaling pathways and their implications in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 2924557-38-8 |
| Applications | Ligand for Target Protein for PROTAC |
| Formula | C24H23N5O |
| Molecular Weight | 397.47 |
| SMILES | O=C(CN1C=C(C2=CC=C(C3=CN=CC4=CC=CC=C43)C=C2)C=N1)N5CCNCC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.