CDK9-IN-14 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9), exhibiting an IC50 value of 6.92 nM. This compound demonstrates significant inhibitory activity against MV4;11 cells and exhibits efficacy in in vivo tumor models. Additionally, CDK9-IN-14 shows favorable selectivity and a low toxicity profile, making it suitable for various cancer research applications aimed at targeting transcriptional regulation pathways.
CDK9-IN-14 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9), exhibiting an IC50 value of 6.92 nM. This compound demonstrates significant inhibitory activity against MV4;11 cells and exhibits efficacy in in vivo tumor models. Additionally, CDK9-IN-14 shows favorable selectivity and a low toxicity profile, making it suitable for various cancer research applications aimed at targeting transcriptional regulation pathways.
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