Fig. 1 · Structure

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CDK9-IN-28

CDK9 Inhibitor

CDK9-IN-28 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9), which plays a critical role in regulating transcription and cell cycle progression. This compound exhibits strong anti-proliferative effects, particularly in solid tumor models, making it valuable for cancer research. Additionally, CDK9-IN-28 serves as a target protein ligand for the synthesis of PROTACs, aiding in the development of innovative therapeutic strategies for targeting CDK9-dependent pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3020773-81-0
Applications CDK9 Inhibitor
Formula C32H40N4O6S2
Molecular Weight 640.81
SMILES
CC(C)(C1=CN=C(O1)CSC2=CN=C(S2)NC(C3CCN(CC3)CCCCCOC4=C5C(OC(C=C5C)=O)=CC(O)=C4)=O)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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