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CDK9-IN-38

CDK9 Inhibitor

CDK9-IN-38 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9), exhibiting IC50 values of 1.2 nM for the wild-type enzyme and 3.3 nM for the L156F mutant variant. This compound has demonstrated significant inhibitory effects on tumor growth in both in vitro and in vivo models. CDK9-IN-38 is a valuable tool for research into the regulation of transcriptional control and the therapeutic potential for cancer treatment.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2773402-44-9
Applications	CDK9 Inhibitor
Formula	C₂₂H₂₃N₅O₃S
Molecular Weight	437.51
SMILES	O=C1NCC(C)(C)C2=CC(C3=NC(NC4=CC=CC(CS(N)(=O)=O)=C4)=NC=C3)=CC=C21

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.