Fig. 1 · Structure

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CDK9 ligand 3

CDK9 Ligand

CDK9 ligand 3 is a selective inhibitor of cyclin-dependent kinase 9 (CDK9), known for its role in regulating transcriptional elongation. It serves as a crucial component in the synthesis of PROTAC CDK9 degrader-11, facilitating targeted protein degradation. This compound is valuable for research applications focused on cancer therapeutics and the modulation of gene expression through CDK9 inhibition.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3039540-24-1
Applications CDK9 Ligand
Formula C18H18BrCl2N5O3
Molecular Weight 503.18
SMILES
O=C(NC1=CNN=C1C(NC2CCN(CC2)C(CBr)=O)=O)C3=C(C=CC=C3Cl)Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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