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CDK9 ligand 5

CDK9 Ligand

CDK9 Ligand 5 is a selective inhibitor of cyclin-dependent kinase 9 (CDK9), a critical regulator of transcriptional control. This compound serves as a valuable ligand for the design and development of PROTACs (Proteolysis Targeting Chimeras) aimed at degrading CDK9, exemplified by the PROTAC CDK9 degrader-9. CDK9 Ligand 5 is particularly relevant in cancer research, where CDK9 activity plays a pivotal role in cell proliferation and survival.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3079792-42-7
Applications	CDK9 Ligand
Formula	C₁₉H₂₇N₇O
Molecular Weight	369.46
SMILES	NC1=CC=C(CNC2=NC(N[C@H](CO)CC)=NC3=C(C(C)C)C=NN32)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

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Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.