Documents & Downloads

CDLI-5

CRBN Degrader-Linker Conjugate

CDLI-5 is a cereblon (CRBN) degrader-linker conjugate designed for the synthesis of cereblon degrader antibody conjugates (cDACs). This compound enables targeted protein degradation through the recruitment of E3 ligases to specific substrates, facilitating effective modulation of protein levels. CDLI-5 serves as a valuable tool in research applications focused on targeted therapies and the development of novel anticancer strategies.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3047549-85-6
Applications	CRBN Degrader-Linker Conjugate
Formula	C₇₃H₈₃F₂N₁₅O₁₅S
Molecular Weight	1480.59
SMILES	CS(CC(C=C12)=C(C(NCCCCCCCNC3=C4C(C(N(C5C(N(C(CC5)=O)CNC(OCC6=CC=C(C=C6)NC([C@H](CCCNC(N)=O)NC(C7(CCC7)C(NCCCCCN8C(C=CC8=O)=O)=O)=O)=O)=O)=O)C4)=O)=CC=C3)=O)C=C2N(C9=C(C=C(C=N9)F)F)CC%10=CNC%11=C%10C1=CN(C)C%11=O)(=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.