Fig. 1 · Structure
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CdnP-IN-1
CdnP Inhibitor
CdnP-IN-1 is a highly selective inhibitor of the Mycobacterium tuberculosis cyclic dinucleotide phosphodiesterase (CdnP), exhibiting an IC50 value of 18 μM. This non-nucleotide compound selectively targets CdnP without affecting the enzymatic activities of other bacterial cyclic dinucleotide phosphodiesterases, such as Yybt, RocR, and GBS-CdnP, nor does it inhibit the viral phosphodiesterase poxin or mammalian ENPP1. CdnP-IN-1 is valuable for research applications aimed at elucidating the role of cyclic dinucleotides in Mycobacterium tuberculosis pathogenesis and potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 691862-35-8 |
| Applications | CdnP Inhibitor |
| Formula | C17H17N3O3S |
| Molecular Weight | 343.40 |
| SMILES | O=C1C2=C(N=CN1CC(NC3=C(OC)C=CC=C3)=O)SC(CC)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.