Fig. 1 · Structure

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CEase-IN-1

CEase Inhibitor

CEase-IN-1 (Compound A1H3) is a potent and selective inhibitor of cholesterol esterase (CEase), exhibiting an IC50 of 0.36 μM. This compound is valuable for investigating the role of CEase in the regulation of cholesterol levels and may aid in the research of hypercholesterolemia and related metabolic disorders. Its specificity makes it an effective tool for elucidating the biochemical pathways influenced by cholesterol metabolism.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2985688-68-2
Applications CEase Inhibitor
Formula C13H15F3N2O2
Molecular Weight 288.27
SMILES
O=C(COC1=CC=C(C(F)(F)F)C=C1)N/N=C/CCC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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