Fig. 1 · Structure
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Cedazuridine
CDA Inhibitor
Cedazuridine is an orally active inhibitor of cytidine deaminase (CDA), exhibiting an IC50 value of 0.4 μM. This compound is significant in cancer research, as it helps to elucidate the role of CDA in nucleoside metabolism and tumor progression. Its ability to impair CDA activity makes it a valuable tool for investigating therapeutic strategies in oncology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1141397-80-9 |
| Applications | CDA Inhibitor |
| Formula | C9H14F2N2O5 |
| Molecular Weight | 268.21 |
| Synonyms | E7727 |
| SMILES | O[C@H]1C(F)(F)[C@H](N(CC[C@@H](O)N2)C2=O)O[C@@H]1CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
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| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.