Cediranib maleate

Catalog No.: A21857

VEGFR inhibitor

Cediranib maleate

Cediranib maleate Chemical Structure

CAS NO. 857036-77-2

Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.

Availability: In stock

Package Price Qty
5 mg
$65.00
10 mg
$112.00
50 mg
$331.00
100 mg
$662.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.
In vitro DMSO 92 mg/mL (162.37 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.65 mL 88.25 mL 176.5 mL
0.5 mM 3.53 mL 17.65 mL 35.3 mL
1 mM 1.76 mL 8.82 mL 17.65 mL
5 mM 0.35 mL 1.76 mL 3.53 mL

*The above data is based on the productmolecular weight 566.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21857
Actions Inhibitor
CAS No. 857036-77-2
Formula C29H31FN4O7
M. Wt 566.58
Purity >98%
Synonyms AZD-2171 maleate, AZD2171, AZD 2171
SMILES O=C(O)/C=C\C(O)=O.FC1=C(OC2=C(C(C=C3OCCCN4CCCC4)=NC=N2)C=C3OC)C=CC5=C1C=C(C)N5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Cediranib maleate | Cediranib maleate Supplier | purchase | cost | manufacturer | order | distributor | buy 857036-77-2| 857036-77-2 Supplier | purchase 857036-77-2 | 857036-77-2 cost | 857036-77-2 manufacturer | order 857036-77-2 | 857036-77-2 distributor
Rewards