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VEGFR inhibitor
In Stock
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| Target | Activity | Value |
|---|---|---|
| Flt-1 | IC50 | 5 nM |
| KDR | IC50 | 1 nM |
| Flt-4 | IC50 | 3 nM |
| PDGFRα | IC50 | 36 nM |
| PDGFRβ | IC50 | 5 nM |
| c-Kit | IC50 | 2 nM |
6 targets · Scroll to view more
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 857036-77-2 |
| Applications | VEGFR inhibitor |
| Formula | C29H31FN4O7 |
| Molecular Weight | 566.58 |
| Synonyms | AZD-2171 maleate; AZD2171 |
| SMILES | O=C(O)/C=C\C(O)=O.FC1=C(OC2=C(C(C=C3OCCCN4CCCC4)=NC=N2)C=C3OC)C=CC5=C1C=C(C)N5 |
| Solvent | Reported Solubility |
|---|---|
| DMSO | 92 mg/mL (162.37 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
