Cediranib maleate

Catalog No.: A21857

VEGFR inhibitor

Cediranib maleate

Cediranib maleate Chemical Structure

CAS NO. 857036-77-2

Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.

Availability: In stock

Package Price Qty
5 mg
$65.00
10 mg
$112.00
50 mg
$331.00
100 mg
$662.00
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Biological Activity

Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.65 mL 88.25 mL 176.5 mL
0.5 mM 3.53 mL 17.65 mL 35.3 mL
1 mM 1.76 mL 8.82 mL 17.65 mL
5 mM 0.35 mL 1.76 mL 3.53 mL

*The above data is based on the productmolecular weight 566.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21857
Actions Inhibitor
M. Wt 566.58
Formula C29H31FN4O7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 857036-77-2
Synonyms AZD-2171 maleate, AZD2171, AZD 2171
SMILES O=C(O)/C=C\C(O)=O.FC1=C(OC2=C(C(C=C3OCCCN4CCCC4)=NC=N2)C=C3OC)C=CC5=C1C=C(C)N5

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