Fig. 1 · Structure

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Ceefourin 1

MRP4 Inhibitor

Ceefourin 1 is a selective inhibitor of the multidrug resistance protein 4 (MRP4). This compound effectively inhibits the transport of various MRP4 substrates while demonstrating a high degree of selectivity against other ATP-binding cassette (ABC) transporters. As a benzothiazole derivative, Ceefourin 1 serves as a promising chemosensitizer in the treatment of high-risk neuroblastoma, facilitating enhanced therapeutic efficacy.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 315702-40-0
Applications MRP4 Inhibitor
Formula C11H10N4S3
Molecular Weight 294.42
SMILES
S=C1NN=C(CSC2=NC3=CC=CC=C3S2)N1C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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