Catalog No.: A20858
PLK4 inhibitor
Centrinone (LCR-263) is a selective and reversible inhibitor of polo-like kinase 4 (PLK4) with a Ki of 0.16 nM.
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Centrinone 5mg
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Centrinone 10mg
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Centrinone 50mg
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Centrinone 100mg
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Biological Activity
Discription Centrinone (LCR-263) is a selective and reversible inhibitor of polo-like kinase 4 (PLK4) with a Ki of 0.16 nM.
Target Value
Chemical Information
Catalog Num A20858
Formula C26H25F2N7O6S2
Molecular Weight 633.65
CAS Number 1798871-30-3
SMILES FC(C([N+]([O-])=O)=CC=C1)=C1CS(C2=CC(F)=C(SC3=NC(NC4=NNC(C)=C4)=C(OC)C(N5CCOCC5)=N3)C=C2)(=O)=O
Synonyms LCR-263, LCR 263, LCR263

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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