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CEP-11981 tosylate

Tyrosine Kinase Inhibitor

CEP-11981 tosylate is an orally active tyrosine kinase inhibitor that targets TIE2, VEGFR1-3, and FGFR1. This compound exhibits significant anti-tumor and anti-angiogenic properties, making it valuable for cancer research and therapeutic development. Its ability to modulate key pathways in angiogenesis positions it as a potential candidate for studies aimed at understanding and treating various malignancies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	901128-79-8
Applications	Tyrosine Kinase Inhibitor
Formula	C₃₅H₃₅N₇O₄S
Molecular Weight	649.76
Synonyms	ESK981 tosylate; BOL 303213X tosylate
SMILES	O=S(O)(C1=CC=C(C)C=C1)=O.CC(C)CN(C2=C3C4=C(C(NC4)=O)C5=C2CCC6=NN(C)C=C65)C(C3=C7)=CC=C7NC8=NC=CC=N8

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.