Fig. 1 · Structure
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Cerberin
Cardiac Glycoside
Cerberin is a cardiac glycoside that primarily targets Na+/K+-ATPase, leading to increased intracellular sodium levels and prolonged action potential duration in cardiac cells. This compound exhibits significant cytotoxicity against KB and NCI H187 cancer cell lines, with IC50 values of 1.92 and 1.24 μg/mL respectively. Cerberin's dual activity as both a cytotoxic agent and a cardiac modulator makes it a valuable tool for research in cardiology and oncology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 25633-33-4 |
| Applications | Cardiac Glycoside |
| Formula | C32H48O9 |
| Molecular Weight | 576.72 |
| Synonyms | 2'-Acetylneriifolin |
| SMILES | O[C@@]12[C@@]3([H])[C@@](CC[C@@]1([C@@H](C(CO4)=CC4=O)CC2)C)([H])[C@@]5([C@](C[C@H](CC5)O[C@H]6[C@H]([C@@H]([C@H]([C@@H](O6)C)O)OC)OC(C)=O)([H])CC3)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.