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Ceritinib-amide-C3-acid

Target Protein Ligand-Linker Conjugate

Ceritinib-amide-C3-acid is a targeted protein ligand-linker conjugate that enhances molecular interactions for E3 ligase recruitment. This reagent combines the active component ceritinib with a linker moiety, facilitating the development of targeted protein degradation strategies. Ceritinib-amide-C3-acid is instrumental in synthesizing TD-004, thus offering valuable applications in protein biology and therapeutic research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2162120-74-1
Applications	Target Protein Ligand-Linker Conjugate
Formula	C₃₃H₄₂ClN₅O₆S
Molecular Weight	672.23
SMILES	CC(C)OC(C=C(C1CCN(CC1)C(CCCC(O)=O)=O)C(C)=C2)=C2NC3=NC=C(Cl)C(NC4=C(C=CC=C4)S(C(C)C)(=O)=O)=N3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.