Fig. 1 · Structure
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Cetirizine-d4
H1-receptor Antagonist
Cetirizine-d4 is a deuterium-labeled derivative of Cetirizine, a second-generation antihistamine that selectively antagonizes the histamine H1-receptor. This compound exhibits significant antiallergic properties, effectively inhibiting eosinophil chemotaxis in the context of allergic responses. Cetirizine-d4 is suitable for research applications focused on allergy mechanisms and the pharmacokinetics of antihistamines.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1219803-84-5 |
| Applications | H1-receptor Antagonist |
| Formula | C21H21D4ClN2O3 |
| Molecular Weight | 392.91 |
| SMILES | O=C(O)COC([2H])([2H])C([2H])([2H])N1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.