Fig. 1 · Structure
Documents & Downloads
Cetirizine-d8 dihydrochloride
H1-receptor Antagonist
Cetirizine-d8 dihydrochloride is a deuterium-labeled variant of Cetirizine, a second-generation antihistamine that acts as a selective H1-receptor antagonist. This compound exhibits strong antiallergic properties, effectively inhibiting eosinophil chemotaxis associated with allergic reactions. Cetirizine-d8 is valuable in pharmacokinetic studies and research involving allergic response mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2070015-04-0 |
| Applications | H1-receptor Antagonist |
| Formula | C21H19D8Cl3N2O3 |
| Molecular Weight | 469.86 |
| SMILES | ClC1=CC=C(C(N2C([2H])([2H])C([2H])([2H])N(CCOCC(O)=O)C([2H])([2H])C2([2H])[2H])C3=CC=CC=C3)C=C1.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.