Cetirizine Dihydrochloride

Catalog No.: A10195

Cetirizine Dihydrochloride

Cetirizine Dihydrochloride Chemical Structure

CAS NO. 83881-52-1

Cetirizine is a second-generation antihistamine, a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria.

Availability: In stock

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100 mg

Regular Price: $60.00

Special Price $48.00

200 mg

Regular Price: $85.00

Special Price $68.00

500 mg

Regular Price: $110.00

Special Price $88.00

10mM * 1mL in DMSO

Regular Price: $62.00

Special Price $49.60

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Biological Activity

Cetirizine is a second-generation antihistamine, a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria.
Targets
Histamine receptor
In vitro DMSO 81 mg/mL (175.39 mM)
Water 81 mg/mL (175.39 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.65 mL 108.27 mL 216.54 mL
0.5 mM 4.33 mL 21.65 mL 43.31 mL
1 mM 2.17 mL 10.83 mL 21.65 mL
5 mM 0.43 mL 2.17 mL 4.33 mL

*The above data is based on the productmolecular weight 461.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10195
CAS No. 83881-52-1
Formula C21H25ClN2O3.2HCl
M. Wt 461.81
Purity >98%
SMILES C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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