Documents & Downloads
Cevostamab
Cevostamab (BFCR4350A; RG6160; RO7187797) is a humanized IgG1-based bispecific antibody (BsAb) designed to target the membrane-proximal extracellular domain of FcRH5 on multiple myeloma (MM) cells, as well as CD3 on T cells. This dual targeting promotes efficient synapse formation between T cells and MM tumor cells, enhancing the cytotoxic activity of T cells against the tumor cells. Cevostamab's unique mechanism of action makes it a valuable tool for research in immuno-oncology and the therapeutic targeting of multiple myeloma.
In Stock
Biological Activity
Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2249888-53-5 |
| Molecular Weight | 146190 |
| Synonyms | BFCR 4350A; RG 6160; RO 7187797 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.