Fig. 1 · Structure
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Cf1743
VZVTK Inhibitor
Cf1743 is a bicyclic nucleoside analogue that acts as a specific inhibitor of the varicella-zoster virus thymidine kinase (VZVTK). It displays significant antiviral activity, exhibiting an IC50 value of 3.3 μM against VZV TK. This compound is useful for studying VZV replication and potential therapeutic interventions in herpesvirus infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 319425-66-6 |
| Applications | VZVTK Inhibitor |
| Formula | C22H26N2O5 |
| Molecular Weight | 398.45 |
| SMILES | O=C1N=C2C(C=C(C3=CC=C(C=C3)CCCCC)O2)=CN1[C@@H](C[C@@H]4O)O[C@@H]4CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.