CFI-401980

Catalog No.: A55060
MPS1 Inhibitor
CFI-401980 is a selective inhibitor of the MPS1 kinase, exhibiting an affinity characterized by a Ki value of 0.8 nM. This compound effectively inhibits the proliferation of HCT116 cancer cell lines, making it a valuable tool in cancer research. CFI-401980 may be utilized to investigate the role of MPS1 in cell cycle regulation and its potential as a therapeutic target in anti-cancer strategies.
Grouped product items
Size Price Stock Qty
25mg
$1,780.00
In stock
50mg
$2,280.00
In stock
100mg
$2,960.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCFI-401980 is a selective inhibitor of the MPS1 kinase, exhibiting an affinity characterized by a Ki value of 0.8 nM. This compound effectively inhibits the proliferation of HCT116 cancer cell lines, making it a valuable tool in cancer research. CFI-401980 may be utilized to investigate the role of MPS1 in cell cycle regulation and its potential as a therapeutic target in anti-cancer strategies.
Product Information
Catalog NumA55060
FormulaC28H30N6O3
Molecular Weight498.58
CAS Number1610676-27-1
SMILESO=C(NC1CC1)C2=CC=C(C3=C4N(N=C3)C(NCC5CCOCC5)=NC(OC6=CC=CC=C6)=N4)C=C2C
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
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