CFMMC is a selective allosteric antagonist of the metabotropic glutamate receptor 1 (mGluR1). This compound effectively inhibits L-glutamate-induced intracellular calcium mobilization in Chinese hamster ovary cells expressing recombinant human mGluR1a, with an IC50 value of 50 nM. CFMMC is of particular interest for research into a range of central nervous system disorders, including schizophrenia, epilepsy, anxiety, pain, cognitive dysfunction, and substance abuse.
CFMMC is a selective allosteric antagonist of the metabotropic glutamate receptor 1 (mGluR1). This compound effectively inhibits L-glutamate-induced intracellular calcium mobilization in Chinese hamster ovary cells expressing recombinant human mGluR1a, with an IC50 value of 50 nM. CFMMC is of particular interest for research into a range of central nervous system disorders, including schizophrenia, epilepsy, anxiety, pain, cognitive dysfunction, and substance abuse.
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