Fig. 1 · Structure
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CFMMC
mGluR1 Antagonist
CFMMC is a selective allosteric antagonist of the metabotropic glutamate receptor 1 (mGluR1). This compound effectively inhibits L-glutamate-induced intracellular calcium mobilization in Chinese hamster ovary cells expressing recombinant human mGluR1a, with an IC50 value of 50 nM. CFMMC is of particular interest for research into a range of central nervous system disorders, including schizophrenia, epilepsy, anxiety, pain, cognitive dysfunction, and substance abuse.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1190598-60-7 |
| Applications | mGluR1 Antagonist |
| Formula | C22H28FNO4 |
| Molecular Weight | 389.46 |
| SMILES | O=C1C2=C(OC=C1C3CCCCC3)C=C(OCCN4CCOCC4)C(C)=C2F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.