Fig. 1 · Structure
Documents & Downloads
CFT-1297
BET PROTAC
CFT-1297 is a BET PROTAC degrader that specifically targets and facilitates the degradation of BRD4. This compound enhances the selective elimination of BRD4 protein, which plays a crucial role in regulating gene transcription associated with various cancers. CFT-1297 serves as a valuable tool for researchers investigating the mechanisms of epigenetic regulation and developing targeted therapies for cancer treatment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 2154353-03-2 |
| Applications | BET PROTAC |
| Formula | C47H50ClN9O3 |
| Molecular Weight | 824.41 |
| SMILES | CC1=NN=C2N1C3=C(C(C4=CC=C(C=C4)Cl)=NC25CC5)C=C(C=C3)C6=CN(N=C6)CCCCCCCN7CCC(CC7)C8=CC=CC9=C8CN(C9=O)C%10CCC(NC%10=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.