CFTR corrector 4

Catalog No.: A66473
CFTR Corrector
CFTR Corrector 4 is an (R,R)-form enantiomer that acts as a potent corrector of the cystic fibrosis transmembrane conductance regulator (CFTR). This compound enhances the expression of CFTR at the cellular surface, making it a promising candidate for therapeutic applications in cystic fibrosis research. Its ability to modulate CFTR levels may contribute to correcting defective chloride ion transport associated with the disease.
Grouped product items
Size Price Stock Qty
1mg
$35.00
In stock
5mg
$90.00
In stock
10mg
$140.00
In stock
25mg
$285.00
In stock
50mg
$390.00
In stock
100mg
$540.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCFTR Corrector 4 is an (R,R)-form enantiomer that acts as a potent corrector of the cystic fibrosis transmembrane conductance regulator (CFTR). This compound enhances the expression of CFTR at the cellular surface, making it a promising candidate for therapeutic applications in cystic fibrosis research. Its ability to modulate CFTR levels may contribute to correcting defective chloride ion transport associated with the disease.
Product Information
Catalog NumA66473
FormulaC29H27F2NO7
Molecular Weight539.52
CAS Number1918142-34-3
SMILESO=C(C1(C2=CC=C(OC(F)(F)O3)C3=C2)CC1)N[C@@H]4C[C@H](C5=CC=C(OC)C(OC)=C5)OC6=CC(OC)=CC=C46
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