Fig. 1 · Structure

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CGP 44 645

Metabolite

CGP 44 645 is a methanol metabolite of Letrozole, serving as a molecular marker for assessing the metabolic kinetics of Letrozole in vitro using microsomes. This compound can provide insights into the metabolic profile, particularly highlighting potential sex-specific variations in its levels within rat liver microsomes. Research applications include pharmacokinetic studies and investigations into the metabolism of aromatase inhibitors.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 134521-16-7
Applications Metabolite
Formula C15H10N2O
Molecular Weight 234.25
SMILES
OC(C1=CC=C(C=C1)C#N)C2=CC=C(C=C2)C#N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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