CGP-82996 is a selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6). It demonstrates IC50 values of 1.5 μM, 5.6 μM, and 25 μM against CDK4/cyclin D1, CDK6/cyclin D1, and Cdk5/p35, respectively. This compound effectively induces apoptosis in U2OS cancer cells, making it a valuable tool in cancer research to study the modulation of cell cycle progression and cancer cell viability.
CGP-82996 is a selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6). It demonstrates IC50 values of 1.5 μM, 5.6 μM, and 25 μM against CDK4/cyclin D1, CDK6/cyclin D1, and Cdk5/p35, respectively. This compound effectively induces apoptosis in U2OS cancer cells, making it a valuable tool in cancer research to study the modulation of cell cycle progression and cancer cell viability.
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