Biological Activity
CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.
Targets
HSP90α | ||||
0.48 nM(Kd) |
In vitro | DMSO | 83 mg/mL (199.56 mM) | |
Water | <1 mg/mL (<1 mM) | ||
Ethanol | <1 mg/mL (<1 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.04 mL | 120.22 mL | 240.44 mL |
0.5 mM | 4.81 mL | 24.04 mL | 48.09 mL |
1 mM | 2.4 mL | 12.02 mL | 24.04 mL |
5 mM | 0.48 mL | 2.4 mL | 4.81 mL |
*The above data is based on the productmolecular weight 415.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A14282 |
---|---|
Actions | Inhibitor |
M. Wt | 415.9 |
Formula | C19H18ClN5O2S |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 959763-06-5 |
Synonyms | CH 5138303 |
SMILES | C1C2=CC=CC3=C2C(=CC(=C3C4=NC(=NC(=N4)SCCCC(=O)N)N)Cl)CO1 |
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