Fig. 1 · Structure
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ChemR23-IN-2
ChemR23 Inhibitor
ChemR23-IN-2 is a highly potent inhibitor of ChemR23, exhibiting an IC50 value of 3.2 nM. This compound has demonstrated effective oral bioavailability, making it suitable for in vivo studies. Its primary research applications include investigations into ChemR23-mediated signaling pathways and the modulation of immune responses, contributing to the understanding of various inflammatory conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2465086-50-2 |
| Applications | ChemR23 Inhibitor |
| Formula | C29H26N4O5 |
| Molecular Weight | 510.54 |
| SMILES | OC(C1=CC=CC2=C1N=C(N(CC3CC3)[C@H](C)C4=CC=C(C5=CC(C)=CC=C5C(NO6)=NC6=O)C=C4)O2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.