Fig. 1 · Structure
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ChemR23-IN-4
ChemR23 Inhibitor
ChemR23-IN-4 is a selective inhibitor of the ChemR23 receptor, exhibiting a potent inhibitory effect with an IC50 of 17 nM in human cells. This compound serves as a valuable tool for investigating the role of ChemR23 in various biological processes, including immune response modulation and inflammation. Its oral efficacy makes it suitable for in vivo studies aimed at elucidating the pathway involving ChemR23 signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2465085-23-6 |
| Applications | ChemR23 Inhibitor |
| Formula | C27H26N6O3 |
| Molecular Weight | 482.53 |
| SMILES | CCCCN([C@@H](C1=CC=C(C=C1)C2=CC=CC=C2C3=NN=NN3)C)C4=NC5=C(O4)C=CC=C5C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.