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CHF-6550

β2 Adrenoceptor Agonist

CHF-6550 is a selective β2 adrenoceptor agonist with a pKi of 10.6, demonstrating potent activation of this receptor. In addition, it functions as an antagonist for the muscarinic M3 receptor, with a pKi of 9.3. CHF-6550 exhibits favorable pharmacokinetic properties and efficient hepatocyte clearance in rat models, making it a valuable reagent for studies involving respiratory pharmacology and cardiovascular research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	3052116-62-5
Applications	β2 Adrenoceptor Agonist
Formula	C₄₂H₄₆N₄O₈
Molecular Weight	734.84
SMILES	O=C(C1=CC=C(C=C1)CNC[C@H](O)C2=C3C=CC(NC3=C(C=C2)O)=O)NCCCOC4=CC=CC([C@](O)(C(O[C@H]5CN(CCC5)C)=O)C6=CC=CC=C6)=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.