Fig. 1 · Structure
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Chloraminophenamide
Carbonic Anhydrase Inhibitor
Chloraminophenamide is a potent inhibitor of carbonic anhydrase, demonstrating Ki values of 75 nM for human carbonic anhydrase II (hCA II), 160 nM for bovine carbonic anhydrase IV (bCA IV), and 8400 nM for human carbonic anhydrase I (hCA I). This compound holds promise for antiglaucoma research, owing to its ability to modulate carbonic anhydrase activity, which plays a crucial role in ocular pressure regulation. Its specificity toward hCA II and bCA IV makes it a valuable tool for studying the therapeutic potential in ocular disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 121-30-2 |
| Applications | Carbonic Anhydrase Inhibitor |
| Formula | C6H8ClN3O4S2 |
| Molecular Weight | 285.73 |
| SMILES | O=S(C1=C(Cl)C=C(N)C(S(=O)(N)=O)=C1)(N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.