Fig. 1 · Structure
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Chloramphenicol succinate sodium
Chloramphenicol Prodrug
Chloramphenicol succinate sodium is a prodrug of Chloramphenicol and functions as a P2Y14 receptor inhibitor with an IC50 of 1.585 nM. This compound acts as a competitive substrate and inhibitor of succinate dehydrogenase (SDH), which may contribute to its toxicity profile. It has demonstrated significant inhibitory effects on colitis and is applicable in research areas such as myelosuppression, gray baby syndrome, aplastic anemia, bacterial meningitis, and inflammatory bowel disease.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 982-57-0 |
| Applications | Chloramphenicol Prodrug |
| Formula | C15H15Cl2N2NaO8 |
| Molecular Weight | 445.18 |
| SMILES | O=C(CCC(O[Na])=O)OC[C@H]([C@@H](C1=CC=C(C=C1)[N+]([O-])=O)O)NC(C(Cl)Cl)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.