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Chlorohexane-PEG-clozapine

HaloTag PROTAC Degrader

Chlorohexane-PEG-clozapine is a HaloTag PROTAC degrader that employs clozapine to selectively target and promote the degradation of HaloTag fusion proteins. It effectively reduces luminescence intensity and decreases the protein levels of Halo-Eluc, facilitating the study of target protein dynamics and function. This reagent is valuable for research applications focusing on targeted protein degradation and modulation of protein levels in cellular systems.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3104316-26-6
Applications	HaloTag PROTAC Degrader
Formula	C₂₇H₃₆Cl₂N₄O₂
Molecular Weight	519.51
SMILES	ClCCCCCCOCCOCCN1CCN(C2=NC3=CC(Cl)=CC=C3NC4=CC=CC=C42)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.