Fig. 1 · Structure
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CHNQD-01255
Arf-GEFs Inhibitor
CHNQD-01255 is a selective inhibitor of Arf-GEFs, a family of guanine nucleotide exchange factors involved in regulating intracellular trafficking and cytoskeletal dynamics. This compound exhibits significant anti-hepatocellular carcinoma (HCC) activity, highlighting its potential as a therapeutic agent in liver cancer research. CHNQD-01255 provides an essential tool for studying the role of Arf-GEFs in cancer progression and may contribute to the development of targeted therapies for HCC.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2756173-91-6 |
| Applications | Arf-GEFs Inhibitor |
| Formula | C23H29NO6 |
| Molecular Weight | 415.48 |
| SMILES | O[C@H]1[C@@]2([H])[C@@](/C=C/CCC[C@@H](OC(/C=C/1)=O)C)([H])C[C@@H](C2)OC(OCC3=CN=CC=C3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.