Fig. 1 · Structure
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Cholera toxin B subunit, from vibrio cholerae
Cholera Toxin
Cholera toxin B subunit (CTB), derived from Vibrio cholerae, is a non-toxic component that binds specifically to ganglioside GM1 on cell surfaces. This binding property makes CTB an effective label for identifying microglial cells, known for their enriched GM1 expression, while showing limited utility for oligodendrocytes or astrocytes. Due to its ability to serve as a tracer, CTB is widely employed in immunohistochemical studies of axonal transport and is also utilized as a marker for membrane lipid rafts in various biological research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 131096-89-4 |
| Applications | Cholera Toxin |
| Synonyms | CTB; from vibrio cholerae |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.