Fig. 1 · Structure
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Cholest-5-ene-3ß,22(S)-diol
Oxysterol
Cholest-5-ene-3ß,22(S)-diol, also known as (22S)-Hydroxycholesterol, functions as a biologically active oxysterol. It exhibits significant effects on lipid metabolism by inhibiting weight gain and reducing serum triacylglycerol (TAG) levels in rat models. This compound is valuable for research applications related to metabolic disorders and cholesterol regulation, displaying minimal cytotoxic, oxidative, or inflammatory effects on human prokaryotic leukemia cells.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 22348-64-7 |
| Applications | Oxysterol |
| Formula | C27H46O2 |
| Molecular Weight | 402.65 |
| Synonyms | (22S)-Hydroxycholesterol |
| SMILES | C[C@]12[C@](CC[C@]1([H])[C@H](C)[C@@H](O)CCC(C)C)([H])[C@@](CC=C3C[C@H]4O)([H])[C@@](CC2)([H])[C@]3(CC4)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.