Fig. 1 · Structure

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Cholesterol 24-hydroxylase-IN-2

Cat. No. A69845 CAS 1613481-52-9

CH24H/CYP46A1 Inhibitor

Cholesterol 24-hydroxylase-IN-2 is a potent inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1) with an IC50 value of 5.4 nM. This compound serves as a valuable tool for studying cholesterol metabolism and is particularly useful in imaging studies involving CH24H in mammalian systems. Its ability to selectively inhibit CH24H facilitates research on neurodegenerative diseases and related metabolic pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1613481-52-9
Applications CH24H/CYP46A1 Inhibitor
Formula C20H23FN4O
Molecular Weight 354.42
SMILES
O=C(C1CCN(CC1)C2=C(C3=CC=C(F)C=C3)N=CN=C2)N(C4CC4)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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