Fig. 1 · Structure
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Cholesteryl sulfate sodium
Cholesterol Synthesis Agonist
Cholesteryl sulfate sodium is a cholesterol biosynthesis agonist that targets NPC2. By competitively binding to NPC2, it activates SREBP2, thereby promoting cholesterol synthesis with an EC50 of 50 μM. This compound enhances the self-assembly of Mitoxantrone hydrochloride and contributes to the repair of the intestinal mucosal barrier while inhibiting inflammation through the regulation of serine protease activity and the PKCη signaling pathway. Additionally, cholesteryl sulfate sodium is integral to platelet cell membrane function, supports platelet adhesion, and influences selective protein kinase C isoforms, impacting keratinocyte differentiation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2864-50-8 |
| Applications | Cholesterol Synthesis Agonist |
| Formula | C27H45NaO4S |
| Molecular Weight | 488.70 |
| SMILES | CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OS(=O)(O[Na])=O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.