Fig. 1 · Structure

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Cholic acid anilide

Spore Germination Inhibitor

Cholic acid anilide is a potent spore germination inhibitor targeting Clostridium difficile. This compound exhibits a significant inhibitory effect on spore germination with an IC50 value of 1.8 μM in assays conducted in sodium phosphate media containing 6 mM taurocholate and 12 mM glycine. Cholic acid anilide is a valuable tool for research applications focused on C. difficile infections and understanding its lifecycle.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 6912-96-5
Applications Spore Germination Inhibitor
Formula C30H45NO4
Molecular Weight 483.68
SMILES
O[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(NC4=CC=CC=C4)=O)([C@H](C[C@]2([H])[C@@]5([C@](C[C@@H](CC5)O)([H])C1)C)O)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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