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ChREBPα/14-3-3 regulator-1

ChREBP/14-3-3 Stabilizer

ChREBPα/14-3-3 regulator-1 is a selective stabilizer that enhances the interaction between carbohydrate response element binding protein (ChREBP) and 14-3-3 proteins, with an EC50 of 3.8 μM. This compound has been shown to protect pancreatic β cells from glucolipotoxicity and support the maintenance of cellular function. It serves as a valuable tool in research focused on the pathophysiology of type 2 diabetes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Stabilizer
CAS Number	3067202-14-3
Applications	ChREBP/14-3-3 Stabilizer
Formula	C₁₆H₁₅F₃NO₅P
Molecular Weight	389.26
SMILES	FC1=CC=CC(C(F)(F)CNC(COC2=C(P(O)(O)=O)C=CC=C2)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.