Chrodrimanin B is a potent antagonist of the GABA receptor RDL, primarily sourced from a fungal metabolite. It effectively inhibits GABA-mediated responses with an IC50 of 1.66 nM, demonstrating a peak current amplitude reduction at the RDL channel with an IC50 of 1.13 nM. This meroterpenoid compound exhibits significant insecticidal activity, making it a valuable tool in the study of insect neurobiology and potential pest control applications.
Chrodrimanin B is a potent antagonist of the GABA receptor RDL, primarily sourced from a fungal metabolite. It effectively inhibits GABA-mediated responses with an IC50 of 1.66 nM, demonstrating a peak current amplitude reduction at the RDL channel with an IC50 of 1.13 nM. This meroterpenoid compound exhibits significant insecticidal activity, making it a valuable tool in the study of insect neurobiology and potential pest control applications.
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