Fig. 1 · Structure
Documents & Downloads
Chrodrimanin B
GABAR RDL Antagonist
Chrodrimanin B is a potent antagonist of the GABA receptor RDL, primarily sourced from a fungal metabolite. It effectively inhibits GABA-mediated responses with an IC50 of 1.66 nM, demonstrating a peak current amplitude reduction at the RDL channel with an IC50 of 1.13 nM. This meroterpenoid compound exhibits significant insecticidal activity, making it a valuable tool in the study of insect neurobiology and potential pest control applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 132196-54-4 |
| Applications | GABAR RDL Antagonist |
| Formula | C27H32O8 |
| Molecular Weight | 484.54 |
| SMILES | C[C@@]([C@@](C(C)1C)([H])C[C@@H]2O)(C=CC1=O)[C@@](CC3=C([C@H]([C@H]4C)OC(C)=O)C(C(O4)=O)=C5O)([H])[C@]2(OC3=C5)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.