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Chrolactomycin

Anticancer Agent

Chrolactomycin is an anticancer agent derived from the Streptomyces sp. 569N-3 strain, exhibiting potent cytotoxicity against various cancer cell lines. It displays IC50 values of 1.2 μM for ACHN, 1.6 μM for A431, 0.69 μM for McF-7, and 0.45 μM for T24 cells, highlighting its effectiveness in inhibiting tumor cell proliferation. In addition to its anticancer properties, Chrolactomycin exhibits selective antibacterial activity against Gram-positive bacteria with a minimum inhibitory concentration (MIC) range of 5.2-10.4 μg/mL, making it a valuable compound for both cancer and microbiological research applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	227606-82-8
Applications	Anticancer Agent
Formula	C₂₄H₃₂O₇
Molecular Weight	432.51
SMILES	CO[C@@]12[C@]3([H])[C@@]4(OC2=O)[C@](CCC[C@H](C[C@H]([C@@](C(C1=O)=C)([H])O3)C)C)([H])C=C([C@H](C4)C)C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.